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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG3 All Species: 18.18
Human Site: T154 Identified Species: 33.33
UniProt: P49916 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49916 NP_002302.2 1009 112907 T154 L E R A R A T T K K I E D L T
Chimpanzee Pan troglodytes XP_511409 922 102716 R137 F V T S T N P R K F S G F S A
Rhesus Macaque Macaca mulatta XP_001113780 1009 112805 T154 L E R A R A T T K K I E D L T
Dog Lupus familis XP_548265 991 110592 T155 L E R A R A T T K K I E D L T
Cat Felis silvestris
Mouse Mus musculus P97386 1015 113000 T155 L E R A R A T T K K I E D L T
Rat Rattus norvegicus NP_001012011 943 105425 T155 L E R A R A T T K K I E D L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006215 902 101303 A117 T V Q A K L T A T G Q I S S P
Frog Xenopus laevis NP_001082183 988 110688 L137 D L E G W Q E L Q D C D K E L
Zebra Danio Brachydanio rerio NP_001025345 752 84159
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650187 806 90830 M21 T R L L C N K M A S K G L H N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27474 773 86292
Sea Urchin Strong. purpuratus XP_786357 875 97201 L90 M E E E E K K L I R K N I E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04819 755 84810
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 97.7 89.4 N.A. 87.3 82.4 N.A. N.A. 71.3 68.2 55.7 N.A. 34.9 N.A. 23.3 48.4
Protein Similarity: 100 91.1 98.8 92.2 N.A. 91.3 86.4 N.A. N.A. 78.9 79.6 64.9 N.A. 48.1 N.A. 39.3 62.9
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 13.3 0 0 N.A. 0 N.A. 0 6.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. 26.6 13.3 0 N.A. 0 N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 47 0 39 0 8 8 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 8 0 8 39 0 0 % D
% Glu: 0 47 16 8 8 0 8 0 0 0 0 39 0 16 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 8 0 16 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 39 8 8 0 0 % I
% Lys: 0 0 0 0 8 8 16 0 47 39 16 0 8 0 0 % K
% Leu: 39 8 8 8 0 8 0 16 0 0 0 0 8 39 8 % L
% Met: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 16 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 8 0 0 8 0 0 8 0 8 0 0 0 0 % Q
% Arg: 0 8 39 0 39 0 0 8 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 0 0 8 8 0 8 16 0 % S
% Thr: 16 0 8 0 8 0 47 39 8 0 0 0 0 0 39 % T
% Val: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _